Table 1.

Baseline Characteristics of 1260 STEMI Patients According to sCR Change Pattern

Variable	sCR Stable, n = 1089	sCR Improved, n = 44	P Value	sCr Worsened, n = 127	P Valuea
Age, y	60 ± 12	64 ± 14	0.05	72 ± 12	<0.001
Male sex	891 (82)	34 (77)	0.43	88 (69)	0.003
DM	211 (19)	15 (34)	0.02	39 (31)	0.001
Dyslipidemia	502 (46)	23 (52)	0.44	69 (54)	0.167
Hypertension	441 (41)	22 (50)	0.21	91 (72)	<0.001
Smoking history	568 (52)	20 (45)	0.44	43 (34)	<0.001
Family history of CAD	183 (17)	7 (16)	0.99	8 (6)	0.009
Prior MI	103 (9)	2 (4)	0.42	14 (11)	0.49
No. of narrowed coronary arteries
1	489 (45)	15 (34)	0.49	46 (36)	0.07
2	327 (30)	17 (39)	0.47	34 (27)	0.07
3	268 (25)	12 (27)	0.26	47 (37)	0.003
Time to ED, min	374 ± 659	420 ± 808	0.39	528 ± 577	<0.001
D2B time, min	44 ± 40	44 ± 19	0.87	45 ± 19	0.24
Contrast material amount, mLb	149 ± 18	134 ± 17	0.359	128 ± 52	0.06
Admission eGFR, mL/min/1.73 m2	73 ± 17	50 ± 14	<0.001	55 ± 20	<0.001
Admission sCr, mg/dL	1.11 ± 0.19	1.60 ± 0.40	<0.001	1.34 ± 0.44	<0.001
Peak sCr, mg/dL	1.14 ± 0.20	1.60 ± 0.40	<0.001	2.08 ± 0.97	<0.001
sCr change in hospital, mg/dL	0.03 ± 0.17	−0.40 ± 0.15	<0.001	0.65 ± 0.69	<0.001
sCr at discharge, mg/dL	1.07 ± 0.17	1.19 ± 0.30	0.007	1.64 ± 0.77	<0.001
Duration of hospitalization, d	5.3 ± 2.9	7.0 ± 5.7	0.11	9.4 ± 7.6	<0.001
Peak CPK, U/L	1180 ± 1384	1053 ± 1135	0.84	1231 ± 1438	0.93
Admission CRP, mg/dL	11.3 ± 25.3	29.7 ± 54	0.008	25.8 ± 43.8	<0.001
LVEF, %	48 ± 8	48 ± 11	0.70	43 ± 9	<0.001

Abbreviations: CAD, coronary artery disease; CPK, creatine phosphokinase; CRP, C‐reactive protein; D2B, door‐to‐balloon; DM, diabetes mellitus; ED, emergency department; eGFR, estimated glomerular filtration rate; LVEF, left ventricular ejection fraction; MI, myocardial infarction; sCR, serum creatinine; SD, standard deviation.

Data are presented as mean ± SD or n (%).

^a P value for worsened sCR vs stable sCr.

^bInformation on contrast volume amount was present for only 418 patients.