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. 2014 Dec 8;38(2):124–130. doi: 10.1002/clc.22346

Figure 1.

CLC-22346-FIG-0001-c

A diagrammatic representation of the relative proportion of myocardial substrate utilization. Under resting conditions, fatty acid metabolism contributes to nearly 70% to 75% energy generation, whereas the remaining comes from glucose metabolism (approximately 8% from glycolysis and 18% from oxidative metabolism). Myocardial substrate utilization changes dramatically with the onset of myocardial ischemia, with glycolysis contributing to nearly 50% of the energy production and a significant reduction in fatty acid uptake and metabolism. Courtesy of Dr. Raymond R. Russell, III, Yale University School of Medicine. Abbreviations: ATP, adenosine triphosphate.