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. 2019 Jul 25;46:193–201. doi: 10.1016/j.ebiom.2019.07.041

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© 2019 The Authors. Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — Media-dependent antibiotic activity of MIN and AZM is influenced by bicarbonate. (A) MIC of AZM or MIN required to inhibit 90% of the untreated controls in HCO₃- free medium amended with various concentrations of HCO3-. (B) Bactericidal activity of 2 μg/ml of MIN in HCO₃- free medium amended with various concentrations of HCO₃-. (C) Bactericidal activity of 1 μg/ml of AZM in HCO₃- free medium amended with various concentrations of HCO₃-. All experiments were conducted in triplicate.