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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Urolithiasis. 2018 Feb 1;46(5):459–470. doi: 10.1007/s00240-018-1043-0

Table 5.

Comparison between umbilicated stones or not

Males Females Total
Morphological type First stone Recurrence First stone Recurrence First stone Recurrence
Umbilicated stones with Randall’s plaque
Type Ia alone 1549 954 (38.1)***,b,xx 501 237 (32.1)x 2050 1191 (36.7)****
Mixed types I+II 869 650 (42.8)**,b, ✝✝ 332 171 (34.0) 1201 821 (40.6)✝✝
Mixed types II+I 360 328 (47.7)c, ✝✝✝✝ 108 57 (34.6) 468 385 (45.1)✝✝✝✝
Total 2778 1932 (41.0)**,d,xx 941 465 (33.1)xx 3719 2397 (39.2)*,xx
Stones without any umbilication nor Randall’s plaque
Type Ia alone 1551 781 (33.5)b 674 262 (28.0)xx 2225 1043 (31.9)xx
I+II 1332 825 (38.2)a,xx, ✝✝✝ 548 282 (34.0)x,✝✝ 1880 1107 (37.1)xx,✝✝✝✝
II+I 1433 1105 (43.5)a,✝✝✝✝ 493 323 (39.6)✝✝✝✝ 1926 1428 (42.6)✝✝✝✝
Total 4316 2711 (38.6)c,xx 1715 867 (33.6)xx 6031 3578 (37.2)xx
*

p=0.02;

**

p < 0.01;

***

p < 0.001;

****

p < 0.0001 vs non-umbilicated stones

a

p < 0.05;

b

p < 0.01;

c

p < 0.001;

d

p < 0.0001 vs females

x

p < 0.01;

xx

p < 0.0001 vs mean occurrence of stone recurrence for a given gender

p < 0.05;

✝✝

p < 0.01;

✝✝✝

p < 0.001;

✝✝✝✝

p < 0.0001 vs type Ia stones for a given gender

Stones of mixed types I+II include stones with various subtypes where COM was the main crystalline phase of calcium oxalate. By contrast, stones of mixed types II+I include stones with various subtypes where COD was the main crystalline phase of calcium oxalate.