Table 4. Adjusted odds ratios of Clostridiodes difficile infection occurrence, nested case–control analysis.
| Characteristic |
Subanalysis: recently diagnosed cancer patients and non–cancer patients* |
|||
|---|---|---|---|---|
| Unadjusted OR (95% CI) |
p value |
Adjusted OR (95% CI)† |
p value |
|
| Tumor type | ||||
| None | 1.00 | 1.00 | ||
| Solid | 1.36 (1.22–1.53) | 0.01 | 1.24 (1.10–1.40) | <0.001 |
| Liquid | 2.22 (1.83–2.69) | <0.001 | 1.84 (1.49–2.26) | <0.001 |
| Prior hospitalizations | ||||
|---|---|---|---|---|
| 0 | 1.00 | 1.00 | ||
| 1 | 1.13 (0.96–1.33) | 0.13 | 1.07 (0.91–1.26) | 0.40 |
| 2 | 2.28 (1.94–2.68) | <0.001 | 1.73 (1.44–2.08) | <0.001 |
| 3 | 3.17 (2.60–3.86) | <0.001 | 2.32 (1.86–2.88) | <0.001 |
| 4 | 4.31 (3.48–5.33) | <0.001 | 2.92 (2.29–3.72) | <0.001 |
| >5 | 8.34 (7.00–9.94) | <0.001 | 5.25 (4.21–6.55) | <0.001 |
| Prior skilled nursing facility stay | ||||
|---|---|---|---|---|
| No | 1.00 | 1.00 | ||
| Yes | 3.80 (3.40–4.24) | <0.001 | 1.64 (1.41–1.92) | <0.001 |
*For cancer patients, diagnosis was made during 2009–2010. OR, odds ratio. †Adjusted odds of CDI based on conditional logistic regression model. Adjusted for age, sex, race, geographic region, urban/rural location, prior hospitalizations, and prior skilled nursing facility stays. Separate models were conducted with all patients with a cancer diagnosis during 2006–2010 and noncancer patients, and for recently diagnosed cancer patients (those diagnosed 2009–2010) and noncancer patients.