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. 2019 Aug 13;10:1028. doi: 10.3389/fphys.2019.01028

Table 4.

Summary of findings table.

Population: patients suffering from cACLD (with an LS cut-off of 10 kPa)
Index test: Baveno VI criteria for ruling out VNTs (LS < 20 kPa and platelet count >150 × 109 cells/L)
Reference standard: Variceal screening endoscopy
Outcomes: Safety (i.e., missed VNT rate) and efficacy (i.e., SER)
Outcomes No. of studies (patients) Point estimate (95% confidence interval) Importance Quality of evidence Comments
Missed VNT rate 13 (4,464) 0.3% 0.1–0.6% Critical •••° moderate Downgraded for risk of bias
SER 13 (4,464) 32.8% 24.8–41.4% Important ••°° low Downgraded for risk of bias and inconsistency

cACLD, compensated advanced chronic liver disease; LS, liver stiffness; SER, spared endoscopy rate; VNTs, varices needing treatment.