Supplementary Fig. S1.

Patients with STEMI have a distinct and early increase in SPM levels

Plasma from healthy volunteers (n = 10) and patients with stable CAD (n = 10) and STEMI (n = 15) were collected after MI onset. Repeated samples were drawn from STEMI patients. LM profiles were obtained using LC-MS/MS. (a) Representative multiple reaction monitoring (MRM) chromatograms of the LM identified in healthy controls and patients with stable CAD and STEMI. Peak heights represent the relative levels of each LM. (b) Accompanying MS/MS spectra used for identification of PD1 and PD2_{n-3 DPA}.