Figure 2.

Effect of exercise‐induced HSP72 expression on VIDD. (A) HSP72 protein expression. Representative western blot images are shown to the right of the graph. (B) Diaphragm muscle cross‐sectional area (CSA) of myosin heavy chain (MHC) Types I, IIa, and IIb/x fibres. (C) Diaphragm muscle specific force production. Values are presented as mean ± SD. CON = acutely anaesthetized control; EX‐HSPAO = exercise‐trained animals treated with an antisense oligonucleotide directed against HSP72; EX‐SALINE = exercise‐trained animals treated with saline; MV = mechanical ventilation; SED‐SALINE = sedentary animals treated with saline. * = MV significantly different versus CON within treatment (P < 0.05). ^ = main effects for MV (P < 0.05). # = main effects for treatment (P < 0.05).