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. 2019 Aug 15;13(8):e0007653. doi: 10.1371/journal.pntd.0007653

Table 5. Cox proportional hazard regression by treatment regimen for PKDL; MDAMB as a reference group.

Treatment regimen Unadjusted
hazard ratio (95% CI)
P-value Adjusted
hazard ratio (95% CI)a
P-value
MDAMB 1 1
MF 1.2 (0.5, 2.8) 0.67 1.2 (0.5, 2.9) 0.62
AMB+PMIM 1.4 (0.6, 3.3) 0.45 1.2 (0.5, 2.9) 0.63
SDAMB 2.1 (0.9, 4.6) 0.06 2.0 (0.9, 4.4) 0.08
AMB+MF 2.1 (0.9, 4.7) 0.06 2.3 (1.0, 5.2) 0.04
PMIM 2.5 (1.1, 5.5) 0.02 2.3 (1.0, 5.0) 0.04
PMIM+MF 3.2 (1.5, 6.9) 0.003 3.0 (1.4, 6.5) 0.005

AMB = AmBisome. MDAMB = multidose liposomal amphotericin B (AmBisome). MF = miltefosine. No. = number. PKDL = post-kala-azar dermal leishmaniasis. PMIM = paromomycin intramascular injection. SDAMB = single-dose liposomal amphotericin B (AmBisome). VL = visceral leishmaniasis.

a Adjusted covariates: Age, Gender, Education, Monthly household expenditure, Number of family members in the household, Family member affected by VL in the past, Type of house, Presence of cattle shed, Number of bednets in the household, How often is the bednet used.