Table 7. Cox proportional hazard regression by treatment regimen for VLR.
| Treatment regimen | Unadjusted hazard ratio (95% CI) |
P-value | Adjusted hazard ratio (95% CI)a |
P-value |
|---|---|---|---|---|
| SSG | 1 | — | 1 | — |
| MDAMB | 1.5 (0.3, 7.5) | 0.62 | 1.3 (0.3, 6.3) | 0.78 |
| AMB+PMIM | 2.0 (0.5, 9.1) | 0.35 | 1.9 (0.4, 8.7) | 0.39 |
| PMIM+MF | 2.7 (0.7, 11.4) | 0.17 | 2.2 (0.5, 9.2) | 0.30 |
| AMB+MF | 3.9 (1.0, 14.9) | 0.05 | 3.5 (0.9, 13.5) | 0.07 |
| SDAMB | 4.6 (1.3, 16.8) | 0.02 | 3.5 (1.0, 13.0) | 0.06 |
| MF | 8.9 (2.7, 29.6) | <0.0001 | 7.5 (2.2, 25.6) | 0.001 |
| PMIM | 8.7 (2.5, 30.0) | 0.001 | 7.7 (2.2, 27.1) | 0.001 |
AMB = AmBisome. MDAMB = multidose liposomal amphotericin B (AmBisome). MF = miltefosine. PMIM = paromomycin intramascular injection. SDAMB = single-dose liposomal amphotericin B (AmBisome). SSG = sodium stibogluconate. VL = visceral leishmaniasis. VLR = visceral leishmaniasis relapse.
a Adjusted covariates: Age, Gender, Education, Monthly household expenditure, Number of family members in the household, Family member affected by VL in the past, Type of house, Presence of cattle shed, Number of bednets in the household, How often is the bednet used.