Table 6.
Follow-up of CAT, markers for systemic inflammation and lung function in the antibiotic group
| Variables | Baseline | 30 days follow-up | 6 months follow-up | P-value |
|---|---|---|---|---|
| CAT | 19.5 (7.2) | 15.5 (5.9) | 0.139 | |
| Systemic inflammation | ||||
| CRP (mg/L) | 6.1 (1.6–9.5) | 3.0 (1.6–1.6) | 5.5 (1.6–5.8) | 0.306 |
| FIB (g/L) | 5.7 (3.1–8.2) | 4.1 (3.1–3.9) | 4.9 (3.1–8.8) | 0.583 |
| IL-8 (pg/mL) | 37.8 (9.0–23.9) | 10.1 (5.1–14.6) | 8.5 (3.5–10.7) | 0.057 |
| Lung function | ||||
| FEV1 (% pred) | 43.8 (15.7) | 43.0 (15.5) | 44.8 (14.9) | 0.951 |
| FVC (% pred) | 59.1 (13.8) | 59.7 (14.4) | 63.2 (11.3) | 0.711 |
| FEV1/FVC | 57.2 (13.2) | 57.8 (12.6) | 57.0 (13.5) | 0.986 |
Note: Data are presented as mean (SD) or median (range).
Abbreviations: CAT, chronic obstructive pulmonary disease assessment test; CRP, C-reactive protein; FIB, fibrinogen; IL-8, interleukin-8; FEV1 (% pre), forced expiratory volume in one second (percentage of predicted); FVC (% pre), forced vital capacity (percentage of predicted); FEV1/FVC, ratio of forced expiratory volume in one second to forced vital capacity.