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SDHD promoter mutation identification in multiple melanoma tumors datasets and cell lines. The frequencies of SDHD promoter mutations are identified from whole-genome and –exome sequencing data of 470 TCGA SKCM, 213 Yale, and 122 Broad melanoma tumors, as well as 99 melanoma cell lines. Most recurrent mutations (colored in red) within each dataset are located within or adjacent to three consensus ETS transcription binding motifs (“TTCC”, colored in green).
