Table 1.

Urinary metabolites (formate, acetate) of saturated aldehydes (formaldehyde, acetaldehyde) as biomarkers of exposure to tobacco products aerosols in mice.

Prod.:Metab.	Air Control (bsl)	Post-Exp. 0–3h	Delta Change 0–3h-bsl	Post-Exp. 3–16h
e-cig CT:formate	3.094±0.344	3.077±0.232	0.791±0.213	4.546±0.338
e-cig MM:formate	2.535±0.451	2.499±0.403	0.230±0.312	3.041±0.128
MCS: formate	3.857±0.635	3.065±0.335	--	5.722±0.734
e-cig CT:acetate	7.227±1.331	9.430±0.823	3.337±0.825	31.670±6.577
e-cig MM:acetate	6.349±0.965	17.620±2.205	6.003±2.682	14.355±1.601
MCS: acetate	7.788±0.860	11.518±0.687	--	24.451±3.962

Abbr: bsl, baseline; Post-Exp., timed urine collection post 6h exposure; Delta Change 0–3h, Post-Exp 0–3h level minus bsl level; e-cig CT, Classic Tobacco; e-cig MM, Magnificent Menthol; MCS, mainstream cigarette smoke of KY Reference cigarette, 3R4F; --, below zero due to high variability and low n. Values = means±SE in ng/mg creatinine; n=5 for e-cig products and n=3 for MCS. No statistically significant differences obeserved between e-cig CT vs e-cig MM.