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. Author manuscript; available in PMC: 2020 Sep 15.
Published in final edited form as: Bioorg Med Chem Lett. 2019 Jul 16;29(18):2686–2689. doi: 10.1016/j.bmcl.2019.07.024

Figure 3.

Figure 3.

Diastereomers of analogue 19. Absolute configuration of the spirocyclic stereocenter determined by both VCD and optical rotations (See supporting information for details).