Fig. 3.

Optical Coherence Tomography (OCT) of the right eye during the most recent presentation. An infrared photo (A) shows the location at which the OCT cuts were obtained. Vertical cuts through the central macula demonstrate the initial lack of response to anti-infectious therapy (B, C), response to intravitreal methotrexate (D, E, F), recurrence of disease after increasing the methotrexate injection interval (G), and eventual resolution after re-treatment with frequent intravitreal methotrexate injections without antivirals or antibiotics (H).