Fig. 4.

PLXNA1 is a target gene of miR-134. (a) the sequence of miR-134 binding to PLXNA1 predicted using the biological prediction online resource microRNA.org; (b) the luciferase activities of PLXNA1-Wt and PLXNA1-Mut in response to miR-134 upregulation; ^⁎p < .05 vs. the NC group (cells transfected with NC plasmid). Measurement data were expressed as mean ± standard error of mean, and analysed by unpaired t-test; the experiment was repeated three times. miR-134, microRNA-134; PLXNA1, plexin A1; NC, negative control; Wt, wild-type; Mut, mutant.