Table 2.

Univariate and multivariate analyses of the prognostic factors of overall survival in the LUAD and LUSC patients.

Characteristic		Univariate analysis			Multivariate analysis
		HR	P	95% CI	HR	P	95% CI
LUAD	SYT7 expression	1.920	0.012⁎	1.158–3.186	1.823	0.046⁎	1.009–3.292
	Low vs High
	Gender	0.639	0.082	0.386–1.058
	Male vs Female
	Age at diagnosis (years)	1.042	0.871	0.534–1.713
	≤60 vs >60
	Smoking status	1.598	0.774	1.023–1.984
	No smoking vs Smoking
	Primary tumor location	1.077	0.772	0.653–1.776
	Left lung vs Right lung
	Differentiation grade	0.871	0.622	0.664–1.985
	High and Middle vs Low
	Primary tumor size	1.987 2.455	0.070 0.032	0.946–4.173 1.082–5.571
	T1 vs T2 vs T3 + T4
	Lymph node metastasis	2.483	0.001⁎⁎	1.483–4.157
	N0 vs N1–3
	Stage Grouping with TNM	3.423	<0.001⁎⁎⁎	1.860–6.299	3.202	<0.001⁎⁎⁎	1.735–5.909
	I + II vs III + IV
LUSC	SYT7 expression	2.067	0.044⁎	1.020–4.188	2.329	0.022⁎	1.132–4.788
	Low vs High
	Gender	0.975	0.942	0.448–1.946
	Male vs Female
	Age at diagnosis (years)	2.397	0.072	0.924–6.217	2.736	0.040⁎	1.047–7.153
	≤60 vs >60
	Smoking status	0.684	0.296	0.335–1.395
	No smoking vs Smoking
	Primary tumor location	0.803	0.533	0.403–1.602
	Left lung vs Right lung
	Differentiation grade	1.410	0.365	0.670–2.966
	High and Middle vs Low
	Primary tumor size	1.333	0.436	0.646–2.751
	T1 + T2 vs T3 + T4
	Lymph node metastasis	0.989	0.984	0.334–2.927
	N0 vs N1–3
	Stage Grouping with TNM	1.950	0.074	1.064–4.685
	I + II vs III + IV

LUAD: lung adenocarcinoma; LUSC: lung squamous cell carcinoma; HR: hazard ratio; CI: confidence interval; TNM: tumor node metastasis.

^⁎P < .05, ^⁎⁎P < .01, ^⁎⁎⁎P < .001, the univariate and multivariate Cox regression analysis.