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. 2019 Aug 27;5:131. doi: 10.1038/s41420-019-0211-5

Fig. 4. Effects of DOX, CPT or BTZ on nuclear localization of p53 in LNCaP cells.

Fig. 4

a Protein levels of p53, lamin, and GAPDH in nucleus and cytoplasm in LNCaP cells treated with 0.2 and 1 μM of DOX for 24 h were analyzed by immunoblotting. b Protein levels of p53, lamin and GAPDH in nucleus and cytoplasm in LNCaP cells treated with 0.5 and 1 μM of CPT for 24 h was analyzed by immunoblotting. c Protein levels of p53, lamin, and GAPDH in nucleus and cytoplasm in LNCaP cells treated with 0.01 and 0.05 μM of BTZ for 36 h was analyzed by immunoblotting. The quantitative ratio of nucleus (N) to cytosol (c) is shown on the right side. *p < 0.05 vs control, **p < 0.01 vs control