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Prevalence of circling behavior in mice with different Zpld1 genotypes.
| Zpld1 genotypes | ||||||
|---|---|---|---|---|---|---|
| +/cwh | cwh/cwh | +/sprl | sprl/sprl | −/− | −/sprl | |
| Total number of mice | 37 | 25 | 12 | 75 | 26 | 63 |
| Number that circle | 1 | 25 | 0 | 36 | 0 | 17 |
| Penetrance of circling | 3% | 100% | 0% | 48% | 0% | 27% |
All mice examined were on a primarily C57BL/6 strain background. Zpld1 genotypes of all mice were determined by DNA analysis.
