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. 2019 Aug 27;9:12444. doi: 10.1038/s41598-019-48925-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Sample dendrogram and trait heatmap. The dendrogram plotted by hierarchical clustering for gastric microbiome composition in 83 included participants. The heatmap presented below the dendrogram indicates clinical traits for the corresponding participants. ABCD group indicates categorization by H. pylori infection and atrophic gastritis as follows: (1) Group A: no H. pylori infection and no atrophic gastritis, (2) Group B: H. pylori infection and no atrophic gastritis, (3) Group C: H. pylori infection and atrophic gastritis with intestinal metaplasia, and (4) Group D: atrophic gastritis with intestinal metaplasia and no H. pylori infection. BMI, body mass index; PG, pepsinogen.