Table 1.
Baseline patient characteristics and microbiome reads of samples.
| Variable | Value |
|---|---|
| n | 83 |
| Age, year, mean ± SD | 40.1 ± 17.5 |
| Sex, n (%) | |
| Male | 39 (47.0) |
| Female | 44 (53.0) |
| Body mass index, kg/m2, mean ± SD | 22.7 ± 3.7 |
| Smoking habit, n (%) | |
| Never | 55 (66.3) |
| Former | 13 (15.7) |
| Current | 15 (18.1) |
| Charlson comorbidity index, n (%) | |
| 0 | 76 (91.6) |
| 1 | 5 (6.0) |
| 2 | 1 (1.2) |
| 3 | 1 (1.2) |
| H. pylori infection, n (%) | 26 (31.3) |
| IgG anti-H. pylori antibody, n (%) | |
| Negative | 59 (71.1) |
| Equivocal | 4 (4.8) |
| Positive | 20 (24.1) |
| Pepsinogen testing, mean ± SD | |
| Pepsinogen I, ng/mL | 62.2 ± 40.8 |
| Pepsinogen II, ng/mL | 17.1 ± 13.0 |
| Pepsinogen I/II ratio | 4.2 ± 1.7 |
| ABCD group | |
| Group A (no H. pylori infection, no atrophic gastritis and metaplasia) | 48 (57.8) |
| Group B (H. pylori infection, no atrophic gastritis and metaplasia) | 14 (16.9) |
| Group C (H. pylori infection, atrophic gastritis and metaplasia) | 12 (14.5) |
| Group D (no H. pylori infection, atrophic gastritis and metaplasia) | 9 (10.8) |
| Microbiome reads, mean ± SD | |
| Read count | 11719.7 ± 7798.1 |
| OTU | 233.0 ± 143.9 |
| Chao1 estimator | 133.4 ± 58.9 |
| Shannon’s diversity index | 2.96 ± 1.36 |
| Simpson’s diversity index | 0.76 ± 0.32 |
OTU, operational taxonomic unit; SD, standard deviation.