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. 2019 Jul 24;4(4):495–505. doi: 10.1016/j.jacbts.2019.03.004

Figure 2.

Figure 2

Histological Findings in WT and MUT Porcine Extracellular Matrix

(A and B) Representative micrographs of wild-type (WT) and mutant (MUT) tissue sections stained with Sirius Red. (C) Masson trichrome–stained tissue showed statistically significant increase in fibrosis fraction in MUT samples (n = 27) compared with WT samples (n = 41). (D) Quantification of Sirius red–labeled tissue also exhibited a statistically significant increase in fibrosis fraction in MUT samples (n = 11) compared with WT samples (n = 18). ****p < 0.0001.