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. 2019 Jul 24;4(4):495–505. doi: 10.1016/j.jacbts.2019.03.004

Figure 5.

Figure 5

Calcium Dynamics of EHTs Created From WT and Mutant Tissue Scaffolds

(A) Representative calcium transient traces measured in EHTs created from WT and MUT ECMs. (B) R403Q mutant ECM EHTs showed a 29% increase in time to peak calcium (CaTTP; p = 0.0087). (C) Time from peak to 80% calcium transient magnitude did not differ (CaRT20; p = 0.70). (D) Decay time constant from 80% peak calcium showed a trend toward being faster in the R403Q mutant ECM EHTs but did not significantly differ (Tau80; p = 0.07). (E) Peak change of calcium transient was not different (RMag; p = 0.70). ∗∗p < 0.01. Abbreviations as in Figures 1, 2, and 4.