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. 2019 Aug 21;10:1963. doi: 10.3389/fimmu.2019.01963

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Copyright © 2019 Pesce, Belgrano, Greppi, Carlomagno, Squillario, Barla, Della Chiesa, Di Domenico, Mavilio, Moretta, Candiani, Sivori, De Cian and Marcenaro.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationship between NKp30 or CD16 expression on PF-NK cells and soluble factor's concentration in the PF of low-grade and high-grade PC patients. Relationship between NKp30 or CD16 receptor downregulation on PF-NK cells and TGF-beta1 concentration in the PF of low-grade PC patients ( dots, n = 3: Pt. 1, Pt. 6, Pt. 8) or high-grade PC patients ( dots, n = 2: Pt. 2, Pt.3). The linear regression line is shown (NKp30 vs. TGF-beta1: R = 0.52 and p = 0.17; CD16 vs. TGF-beta1: R = 0.68 and p = 0.09) (A). Histograms showing the expression of NKp30 on PF-NK cells of a representative low-grade PC patient (Pt. 6) and a representative high-grade PC patient (Pt. 2) and TGF-beta1/sB7-H6 concentration in PF of the same patients (B).

Inline graphic — Relationship between NKp30 or CD16 expression on PF-NK cells and soluble factor's concentration in the PF of low-grade and high-grade PC patients. Relationship between NKp30 or CD16 receptor downregulation on PF-NK cells and TGF-beta1 concentration in the PF of low-grade PC patients ( dots, n = 3: Pt. 1, Pt. 6, Pt. 8) or high-grade PC patients ( dots, n = 2: Pt. 2, Pt.3). The linear regression line is shown (NKp30 vs. TGF-beta1: R = 0.52 and p = 0.17; CD16 vs. TGF-beta1: R = 0.68 and p = 0.09) (A). Histograms showing the expression of NKp30 on PF-NK cells of a representative low-grade PC patient (Pt. 6) and a representative high-grade PC patient (Pt. 2) and TGF-beta1/sB7-H6 concentration in PF of the same patients (B).