Table 1.
Soluble factors detected in plasma and peritoneal fluid (PF) of low-grade and high-grade PC patients compared with soluble factors detected in healthy donors (HD) plasma.
| Patient | Sample | VEGF | TRAIL | TNF-b | TNF-a | SDF-1a | SCGF-b | SCF | RANTES | PDGF-bb | MIP-1b | MIP-1a | MIG | MIF | MCP-3 | MCP-1 (MCAF) | M-CSF |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HD 1 | Plasma | 10.28 | 160.055 | 460.8 | 88.565 | 695.965 | 202488.01 | 32.35 | ND | 20667.39 | 258.245 | 1.96 | 2364.995 | 1895.435 | 0.22 | 11.435 | 30.97 |
| HD 2 | Plasma | 199.075 | 138.935 | 396.9 | 111.785 | 789.445 | 124500.015 | 52.735 | ND | 23018.27 | 280.365 | 1.17 | 339.63 | 2471.425 | 0 | 24.26 | 58.335 |
| Pt. 1 | Plasma | 173.225 | 49.87 | 233.2 | 20.44 | 351.98 | 38700.6 | 6.91 | 2152.38 | 175.59 | 131.345 | 0.865 | 476.08 | 25.89 | 0 | 29.38 | 6.29 |
| Pt. 2 | Plasma | 26.26 | 27.05 | 85.2375 | 2.855 | 113.3075 | 22372.235 | 7.2675 | 1001.33 | 52.9575 | 59.7825 | 1.01 | 240.6425 | 138.35 | 0.11 | 51.6375 | 1.5825 |
| Pt. 3 | Plasma | 0 | 11.875 | 38.81 | 0.94 | 24.585 | 116900.705 | 7.74 | 296.505 | 84.65 | 59.86 | 1.91 | 822.31 | 194.72 | 1.82 | 580.605 | 13.38 |
| Pt. 4 | Plasma | 182.73 | 101.465 | 289.27 | 29.755 | 471.935 | 61759.515 | 16.055 | 2810.5 | 217.905 | 159.76 | 0.85 | 669.645 | 1420.815 | 0 | 114.295 | 5.475 |
| Pt. 6 | Plasma | 0 | 132.93 | 246.78 | 56.61 | 606.365 | 79799.94 | 69.865 | 6180.09 | 304.16 | 144.87 | 3.085 | 4405.87 | 853.22 | 2.415 | 137.95 | 48.335 |
| Pt. 7 | Plasma | 149.805 | 119.5 | 280.45 | 24.905 | 461.575 | 42892.27 | 23.43 | 6357.5 | 748.89 | 172.025 | 0.96 | 665.3 | 940.995 | 0.42 | 96.775 | 19.64 |
| Pt. 8 | Plasma | 0 | 107.385 | 285.975 | 36.42 | 534.265 | 83015.745 | 26.33 | 11953.38 | 403.195 | 169.9 | 1.315 | 418.4 | 1305.49 | 0 | 68.695 | 0 |
| Pt. 1 | PF | 243.795 | 32.4 | 45.635 | 40.81 | 1312.535 | 204341.7 | 51.31 | 309.675 | 94.265 | 60.275 | 6.34 | 1723.75 | 361.75 | 3.515 | 66.62 | 21.815 |
| Pt. 2 | PF | 0 | 20.395 | 36.855 | 9.275 | 156.17 | 2373.91 | 5.37 | 327.12 | 39.58 | 28.25 | 1.235 | 85.095 | 1631.79 | 0 | 19.845 | 0.88 |
| Pt. 6 | PF | 206.17 | 161.195 | 70.05 | 272.79 | 1939.845 | 180303.03 | 71.175 | 75.25 | 170.66 | 244.47 | 133.45 | 10117.56 | 17280.6 | 454.985 | ND | 41.475 |
| Pt. 8 | PF | 131.145 | 25.785 | 39.775 | 57.16 | 1165.935 | 76851.885 | 38.05 | 171.555 | 56.12 | 88.06 | 12.32 | 488.88 | 5486.46 | 6.9 | 145.96 | 4.87 |
| Patient | Sample | LIF | IP-10 | IL-9 | IL-8 | IL-7 | IL-6 | IL-5 | IL-4 | IL-3 | IL-2Ra | IL-2 | IL-1ra | IL-1b | IL-1a | IL-18 | IL-17 |
| HD 1 | Plasma | 4.23 | 1918.885 | 421.4 | 233.155 | 51.89 | 2.21 | 0 | 4.74 | 0 | 118.125 | 0 | 426.365 | 2.12 | 9.32 | 101.44 | 4.71 |
| HD 2 | Plasma | 3.14 | 2095.385 | 352.525 | 97.61 | 146.895 | 6.38 | 0 | 9.055 | 0 | 69.145 | 0 | 1751.08 | 6.075 | 8.505 | 100.32 | 14.895 |
| Pt. 1 | Plasma | 13.995 | 400.91 | 223.48 | 4.66 | 12.615 | 0.955 | 0 | 2.265 | 0 | 43 | 0 | 0 | 0.645 | 5.435 | 9.695 | 0 |
| Pt. 2 | Plasma | 5.5275 | 186.65 | 88.1125 | 7.0725 | 2.26 | 0.53 | 0 | 1.405 | 0 | 23.8325 | 0 | 33.89 | 0.635 | 2.4325 | 7.44 | 0 |
| Pt. 3 | Plasma | 6.375 | 0 | 34.63 | 60.44 | 0 | 277.05 | 0 | 1.025 | 0 | 60.31 | 0 | 259.99 | 0.71 | 4.865 | 18.775 | 0 |
| Pt. 4 | Plasma | 0 | 788.26 | 266.22 | 50.34 | 0.605 | 21.285 | 0 | 4.47 | 0 | 45.6 | 0 | 375.455 | 1.11 | 0 | 13.435 | 0 |
| Pt. 6 | Plasma | 0.58 | 1033.445 | 222.565 | 19.42 | 0 | 19.555 | 7.855 | 2.79 | 0 | 539.595 | 0 | 127.415 | 0.825 | 8.28 | 98.205 | 1.065 |
| Pt. 7 | Plasma | 0 | 93.41 | 296.04 | 33.58 | 36.3 | 25.775 | 8.875 | 1.635 | 0 | 51.59 | 0 | 31.2 | 0.8 | 4.865 | 14.865 | 0 |
| Pt. 8 | Plasma | 110.9 | 440.87 | 262.735 | 14.55 | 9.07 | 0.845 | 0 | 1.205 | 0 | 81.025 | 0 | 116.585 | 0.075 | 1.035 | 18.46 | 0 |
| Pt. 1 | PF | 30.495 | 5694.53 | 42.955 | 118.26 | 7.73 | 657.55 | 9.18 | 2.405 | 0 | 509.645 | 1.24 | 39.36 | 0.835 | 9.725 | 14.21 | 3.96 |
| Pt. 2 | PF | 6.17 | 221.97 | 42.48 | 6.35 | 2.645 | 1.87 | 0 | 0.8 | 0 | 8.215 | 0 | 51.89 | 0.295 | 1.215 | 2.065 | 1.44 |
| Pt. 6 | PF | 117.065 | #DIV/0! | 74.45 | 9170.92 | 15.59 | 5494.13 | 55.24 | 11.35 | 1.17 | 1067.33 | 6.665 | 4488.69 | 4.62 | 27.755 | 73.68 | 22.25 |
| Pt. 8 | PF | 60.945 | 1760.75 | 41.615 | 395.75 | 15.505 | 649.12 | 11.445 | 3.63 | 0 | 252.995 | 0.105 | 166.42 | 0.72 | 3.72 | 16.01 | 6.125 |
| Patient | Sample | IL-16 | IL-15 | IL-13 | IL-12p40 | IL-12(p70) | IL-10 | IFN-g | IFN-a2 | HGF | GROa | GM-CSF | G-CSF | FGF b | Eotaxin | CTACK | b-NGF |
| HD 1 | Plasma | 327.035 | 6.97 | 0 | 33.205 | 0.07 | 1.465 | 0 | 3.02 | 2074.565 | 526.38 | 0 | 48.84 | 8.225 | 40.745 | 1716.99 | 1.345 |
| HD 2 | Plasma | 908.425 | 15.375 | 0 | 30.5 | 0 | 1.465 | 40.335 | 2.33 | 2042.815 | 952.65 | 5.325 | 113.035 | 13.66 | 405.53 | 955.815 | 3.4 |
| Pt. 1 | Plasma | 29.68 | 12.625 | 0 | 2.65 | 0.07 | 0.02 | 0 | 0 | 238.33 | 299.14 | 0 | 50.745 | 0.825 | 83.525 | 989.48 | 1.345 |
| Pt. 2 | Plasma | 34.69 | 0 | 0 | 3.0775 | 0 | 1.245 | 0 | 0 | 180.8 | 123.745 | 0 | 33.79 | 1.2375 | 31.3125 | 465.12 | 0 |
| Pt. 3 | Plasma | 6.45 | 0 | 0 | 12.35 | 0.07 | 0 | 125.35 | 4.74 | 2187.025 | 0 | 0 | 54.435 | 2.475 | 21.865 | 79.455 | 0 |
| Pt. 4 | Plasma | 55.1 | 0 | 0 | 0 | 0.88 | 0 | 8.825 | 0 | 424.265 | 317.125 | 0 | 95.745 | 2.475 | 72.93 | 1791.72 | 0 |
| Pt. 6 | Plasma | 171.58 | 329.125 | 0 | 3.57 | 0.07 | 0 | 91.275 | 1.585 | 902.7 | 389.41 | 5.705 | 114.815 | 4.265 | 133.575 | 1452.625 | 5.895 |
| Pt. 7 | Plasma | 81.985 | 194.27 | 0 | 11.07 | 2.985 | 273.685 | 0 | 0 | 443.885 | 443.59 | 4.31 | 65.075 | 3.645 | 129.18 | 755.355 | 9.065 |
| Pt. 8 | Plasma | 84.785 | 0 | 0 | 0 | 0 | 1.465 | 6.32 | 0.955 | 612.41 | 290.065 | 0 | 59.03 | 0.825 | 134.885 | 924.92 | 0 |
| Pt. 1 | PF | 219.89 | 3.39 | 0.145 | 60.135 | 0.59 | 22.765 | 78.11 | 3.7 | 3570.565 | 125.21 | 0 | 145.975 | 5.49 | 15.27 | 1370.125 | 5.345 |
| Pt. 2 | PF | 62.965 | 0 | 0 | 4.51 | 0.02 | 0.54 | 0 | 1.495 | 148.58 | 54.315 | 0 | 23.845 | 41.905 | 8.92 | 115.165 | 0.175 |
| Pt. 6 | PF | 867.895 | 48.965 | 3.055 | 93.975 | 1.715 | 28.525 | 441.335 | 22.48 | 2151.51 | 622.24 | 3.625 | 1747.37 | 13.415 | 59.71 | 1081.29 | 7.54 |
| Pt. 8 | PF | 224.455 | 0 | 1.07 | 51.775 | 0.22 | 69.325 | 54.42 | 5.105 | 2120.91 | 195.885 | 0.315 | 273.885 | 15.695 | 58.47 | 1013.39 | 6.225 |