Table 2. ORs (95% CIs) of type 2 diabetes mellitus associated with sex-specific quintiles of fetuin-A, the Singapore Chinese Health Study.
| Variable | Quintiles of fetuin-A | ||||
|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | Q5 | |
| Male, µg/mL, median (range) | 396 (262–470) | 513 (470–569) | 619 (570–685) | 788 (685–899) | 1,057 (906–1,499) |
| Female, µg/mL, median (range) | 384 (259–454) | 522 (455–588) | 658 (589–721) | 825 (724–938) | 1,125 (938–1,682) |
| Cases/controls | 86/114 | 82/113 | 110/113 | 149/109 | 131/109 |
| Crude model, OR (95% CI) | 1.00 | 1.08 (0.70–1.67) | 1.68 (1.07–2.65) | 2.45 (1.56–3.85) | 2.26 (1.41–3.62) |
| Adjusted modela, OR (95% CI) | 1.00 | 1.21 (0.74–1.97) | 2.10 (1.25–3.51) | 2.09 (1.26–3.48) | 2.06 (1.21–3.51) |
OR, odds ratio; CI, confidence interval.
aAdjusted model: adjusted for age at blood taken (continuous), smoking status (never, ever smoker), alcohol intake (never, weekly or daily), weekly moderate-to-vigorous physical activity levels (<0.5, 0.5 to 3.9, and ≥4 hours/week), education levels (no, primary school, secondary or above), history of hypertension (yes, no), fasting status (yes, no), and body mass index (continuous).