Table 1. Summary of the main characteristics in terms of accuracy, features, and limitations of state-of-the-art CGM sensor devices.
| Manufacturer | CGM system | Accuracy (MARD), % | Calibrations | Sensor lifetime, day | Smart features | Main limitations |
|---|---|---|---|---|---|---|
| Medtronic | Enlite Sensor | 13.6 | Every 12 hr | 6 | Trend arrows, rate-of-change alerts, hypo/hyperglycemic alarms, integration with Medtronic's pumps | Approved only for as an adjunctive device, acetaminophen interference |
| Guardian Sensor 3 | 10.6 (abdomen) 9.1 (arm) | Every 12 hr | 7 | Trend arrows, rate-of-change alerts, hypo/hyperglycemic alarms, integration with Medtronic's pumps | Approved only for as an adjunctive device, acetaminophen interference | |
| Abbott | Freestyle Navigator II | 14.5 | 2, 10, 24, 72 hr after insertion | 5 | Trend arrows, rate-of-change alerts, hypo/hyperglycemic alarms | Approved only in some European countries as adjunctive device |
| Freestyle Libre | 11.4 | No | 14 | Trend arrows | Sensor need to be scanned to get a glucose reading, not recommended for patient with hypoglycemic unawareness, confirmatory SMBG still recommended when specific episodes occur | |
| Freestyle Libre 2 | Not available | No | 14 | Trend arrows, rate-of-change alerts, hypo/hyperglycemic alarms, remote monitoring | Sensor need to be scanned to get a glucose reading, not recommended for patient with hypoglycemic unawareness, confirmatory SMBG still recommended when specific episodes occur | |
| Dexcom | G4 Platinum | 9 | Every 12 hr | 7 | Trend arrows, rate-of-change alerts, hypo/hyperglycemic alarms, remote monitoring | Approved only as an adjunctive device |
| G5 Mobile | 9 | Every 12 hr | 7 | Trend arrows, rate-of-change alerts, hypo/hyperglycemic alarms, remote monitoring, wireless communication with up to 5 devices | Confirmatory SMBG still recommended when specific episodes occur, acetaminophen interference | |
| G6 | 10 | No | 10 | Trend arrows, rate-of-change alerts, hypo/hyperglycemic alarms, remote monitoring, wireless communication with up to 5 devices | Confirmatory SMBG still recommended when specific episodes occur | |
| Senseonics | Eversense | 11.4 | No | 90 | Trend arrows, rate-of-change alerts, hypo/hyperglycemic alarms | The sensor needs to be inserted and removed in doctor's office, approved as adjunctive device in Europe only |
CGM, continuous glucose monitoring; MARD, mean absolute relative difference; SMBG, self-monitoring of blood glucose.