Table 1.
Plasma analytes.
| Plasma analyte | Time | Sham‐LFD | tSCI‐LFD | Sham‐HFD | tSCI‐HFD | Statistics |
|---|---|---|---|---|---|---|
| Mean ± SEM | Mean ± SEM | Mean ± SEM | Mean ± SEM | |||
| NEFA (mEq/L) (fed) | wk12 | 0.79 ± 0.03 | 0.85 ± 0.10 | 0.89 ± 0.08 | 1.07 ± 0.08 | P (diet) = 0.07 |
| NEFA (mEq/L) (fasted) | wk12 | 0.94 ± 0.06 | 1.05 ± 0.05 | 1.08 ± 0.09 | 0.96 ± 0.06 | |
| Phospholipids (mg/dL) (fed) | wk12 | 223.50 ± 9.44 | 208.00 ± 23.72 | 198.20 ± 18.22 | 238.90 ± 25.28 | |
| Phospholipids (mg/dL) (fasted) | wk12 | 95.53 ± 6.30 | 105.70 ± 9.28 | 94.18 ± 3.00 | 80.85 ± 4.10 | P (diet) = 0.069 |
| Β‐hydroxybutyrate (mg/dL) (fed) | wk12 | 0.93 ± 0.14 | 1.36 ± 0.20 | 1.33 ± 0.22 | 1.22 ± 0.20 | |
| B‐hydroxybutyrate (mg/dL) (fasted) | wk12 | 9.44 ± 1.33 | 10.47 ± 0.90 | 11.71 ± 0.89 | 13.41 ± 1.23 | P (diet) < 0.05 |
| Total cholesterol (mg/dL) (fed) | wk12 | 131.20 ± 6.81 | 115.60 ± 9.83 | 111.30 ± 6.15 | 109.10 ± 4.78 | P (diet) = 0.0842 |
| Total cholesterol (mg/dL) (fasted) | wk12 | 103.30 ± 8.21 | 87.97 ± 6.93 | 76.65 ± 4.78 | 72.19 ± 4.24 | P (diet) < 0.01 |
| Total triglycerides (mg/dL) (fed) | wk12 | 429.30 ± 50.29 | 415.50 ± 67.50 | 733.40 ± 120.30 | 689.50 ± 107.60 | P (diet) < 0.01 |
| Total triglycerides (mg/dL) (fasted) | wk12 | 169.90 ± 24.48 | 152.20 ± 35.16 | 184.70 ± 23.70 | 149.00 ± 22.62 | |
| Plasma glucose (fasted) | wk15 | 128.10 ± 9.10 | 130.30 ± 3.81 | 130.60 ± 5.83 | 127.40 ± 4.92 | |
| C‐Peptide (pM) (fasted) | wk16 | 580.30 ± 145.70 | 507.40 ± 104.40 | 928.30 ± 130.20 | 720.90 ± 109.40 | P (diet) < 0.05 |
| Insulin (ng/mL) (fasted) | wk16 | 3.18 ± 0.52 | 3.57 ± 0.79 | 8.01 ± 1.11 | 4.90 ± 1.82 | P (diet) < 0.05 |
| Leptin (ng/mL) (fasted) | wk16 | 10.94 ± 2.15 | 8.57 ± 2.45 | 16.88 ± 1.99 | 12.25 ± 1.84 | P (diet) < 0.05 |
| Hepatic triglycerides (mg/dL) | wk16 | 529.90 ± 70.12 | 555.40 ± 70.18 | 751.50 ± 64.67 | 645.80 ± 66.81 | P (diet) < 0.05 |
| Hepatic cholesterol (mg/dL) | wk16 | 138.50 ± 3.41 | 148.30 ± 4.45 | 153.90 ± 4.53 | 151.20 ± 5.27 | P (diet) = 0.0519 |
| Muscle triglycerides (mg/dL) | wk16 | 512.6 ± 99.17 | 238.5 ± 46.59 | 478.6 ± 89.82 | 499.1 ± 126 | Sham‐LFD versus tSCI‐LFD, P > 0.05 |
| Muscle cholesterol (mg/dL) | wk16 | 200.5 ± 20.91 | 145.8 ± 6.601 | 195.7 ± 22.24 | 193.6 ± 22.87 | Sham‐LFD versus tSCI‐LFD, P > 0.05 |
| Plasma ALT (fasted) | wk16 | 95.93 ± 7.755 | 88.69 ± 7.011 | 88.69 ± 7.011 | 88.81 ± 7.977 | |
| Plasma AST (fasted) | wk16 | 24.51 ± 2.213 | 25.35 ± 1.437 | 27.47 ± 1.24 | 29.89 ± 2.575 | P (diet) < 0.05 |