Table 1.
Hemodynamic criteria |
1. Systolic blood pressure (SBP) of less than 90 mm Hg for >30 minutes, or use of vasopressors/inotropes to maintain SBP greater than 90 mm Hg |
2. Reduced cardiac output (<1.8 L/min/m2), or 2.0‐2.2 L/min/m2 with vasopressor/inotropic support, in presence of elevated pulmonary capillary wedge pressure |
Signs of tissue hypoperfusion |
1. Tachycardia |
2. Pale, cool, and clammy peripheries, prolonged capillary refill time |
3. Oliguria |
4. Altered mental status/confusion |
5. Elevated lactate |
6. Mixed venous saturation of less than 65% |