Table 1. Summary of lncRNAs that regulate radiosensitivity in radiation therapy.

LncRNA	Radiosensitivity	Types of tumor	Mechanism	Molecular target	Reference
LINP1	Down	Cervical cancer	DNA damage repair	N/A	[13]
MALAT1	Down	Cervical cancer	DNA damage repair	miR-145	[15]
	Down	ESCC	DNA damage repair	CKS1	[16]
	Down	NPC	CSC	miR-1/slug	[54]
HOTAIR	Down	Cervical caner	DNA damage repair	p21 protein	[19]
	Down	Pancreatic ductal cancer	Wnt/β-catenin pathway	WIF-1	[25]
	Down	Pancreatic cancer	Autophagy	Atg7	[69]
CRNDE	Down	Lung cancer	DNA damage repair	p21 protein	[20]
BOKAS	Down	ESCC	Wnt/β-catenin pathway	WISP1	[28]
LincRNA-p21	Up	Colorectal cancer	Wnt/β-catenin pathway	N/A	[31]
	Up	Gastric cancer	Wnt/β-catenin pathway	N/A	[32]
	Down	Hepatoma and glioma cancer	Autophagy	N/A	[71]
UCA1	Down	Prostate cancer	P13k/Akt pathway	N/A	[35]
ANCR	Down	NPC	P13k/Akt pathway	N/A	[36]
LincRNA-ROR	Down	Colorectal cancer	Apoptosis	p53/miR-145	[39]
ANRIL	Down	NPC	Apoptosis	miR-125a	[40]
CCAT1	Down	Breast cancer	Apoptosis	miR-148b	[41]
OIP5-AS1	Up	Colorectal cancer	Apoptosis	DYRK1Y/miR-369-3p	[43]
PVT1	Down	Lung cancer	Apoptosis	miR-195	[44]
DGCR5	Down	Laryngeal cancer	Apoptosis	miR-195	[45]
CYTOR	Down	Lung cancer	Apoptosis	miR-195	[46]
NEAT1	UP	NPC	Apoptosis	miR-101-3b	[47]
	Down	NPC	EMT	miR-204/ZEB1	[61]
GAS5	Up	Cervical cancer	Apoptosis	miR-106b	[48]
TALNEC2	Down	Glioma	CSC	N/A	[56]
TUG1	Down	Bladder cancer	EMT	miR-145/ZEB2	[60]
	Down	Bladder cancer	N/A	HMGB	[74]
HULC	Down	Prostate cancer	Autophagy	N/A	[71]
SNHG18	Down	Glioma	N/A	Semaphorin 5A	[73]
SUMO1P3	Down	Hepatocellular cancer	N/A	N/A	[75]
GACAT3	Up	Lung cancer	N/A	TIMP2	[76]

N/A: The corresponding mechanisms and targets are not yet clear, and need further exploration.