Table 5.
Characteristics of patients with early onset POLE category colorectal cancer (age of onset ≤ 50 years)
| N = 7 | |
|---|---|
| Age (years) [median (range)] | 39 (30‐46) |
| Sex | |
| Man | 6 (85.7) |
| Woman | 1 (14.3) |
| Location | |
| Right | 2 (28.6) |
| Left | 5 (71.4) |
| Histology | |
| Well or moderately differentiated | 5 (71.4) |
| Poorly differentiated or mucinous | 2 (28.6) |
| Tumor size (mm) [median (range)] | 60 (45‐158) |
| pT stage | |
| Tis‐T2 | 1 (14.3) |
| T3‐T4 | 6 (85.7) |
| pStage | |
| 0‐II | 5 (71.4) |
| III‐IV | 2 (28.6) |
| Nonsynonymous SNV count [median (range)] | 3344 (1870‐9515) |
| POLE mutation | |
| P286R | 7 (100) |
Values represent numbers (percentages), unless indicated otherwise.
Abbreviation: SNV, single nucleotide variant.