Table 5.
Analysis of association between candidate SNPs and the risk of lung cancer in genetic model
| Variable | Dominate model | Recessive model | Addictive model | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Adjusted ORa (95% CI) P a Study Power | |||||||||
| rs2043449 | 1.23 (0.86‐1.75) | 0.250 | 2.03 (0.50‐8.19) | 0.319 | 1.24 (0.90‐1.71) | 0.194 | |||
| rs2762934 | 0.76 (0.55‐1.04) | 0.087 | 1.50 (0.53‐4.26) | 0.446 | 0.83 (0.62‐1.10) | 0.190 | |||
| rs1570669 | 0.93 (0.72‐1.20) | 0.561 | 1.18 (0.83‐1.66) | 0.352 | 1.01 (0.84‐1.20) | 0.938 | |||
| rs6068816 | 1.17 (0.91‐1.51) | 0.210 | 1.09 (0.73‐1.62) | 0.686 | 1.12 (0.92‐1.35) | 0.257 | |||
| rs2296241 | 0.98 (0.75‐1.27) | 0.856 | 0.99 (0.72‐1.35) | 0.925 | 0.98 (0.82‐1.18) | 0.862 | |||
| rs1065852 | 1.36 (1.03‐1.80) | 0.030* | 0.868 | 1.64 (1.22‐2.20) | 0.001* | 0.997 | 1.34 (1.13‐1.60) | 0.001* | 0.879 |
*P ≤ 0.05 value indicates statistical significance; P a adjusted for age and sex/
Bold indicates the siginificant value P ≤ 0.05 and the value of study power>0.8
Abbreviations: CI, confidence interval; ORs, odds ratios; SNP, single nucleotide polymorphism.