Table 7.
Variable |
CYP24A1 rs2762934
Adjusted OR (95%CI) P a Study Power |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
AA | AG | GG (AA/AG) vs GG | AA vs (AG/GG) | AA vs GG | ||||||
Sex | ||||||||||
Male | 0.77 (0.20‐2.89) 0.693 | 0.68 (0.46‐0.99) 0.046* | 0.919 | 1.00 | 0.68 (0.47‐0.99) 0.044* | 0.932 | 0.82 (0.22‐3.08) 0.766 | 0.72 (0.51‐1.01) 0.057 | ||
Female | 4.73 (0.54‐41.3) 0.160 | 0.84 (0.42‐1.68) 0.630 | 1.00 | 1.02 (0.54‐1.96) 0.942 | 4.86 (0.56‐42.33) 0.153 | 1.18 (0.68‐2.03) 0.560 | ||||
TNM Stage | ||||||||||
I‐II | 0.58 (0.07‐4.90) 0.615 | 0.72 (0.42‐1.23) 0.228 | 1.00 | 0.71 (0.42‐1.20) 0.202 | 0.61 (0.07‐5.18) 0.651 | 0.73 (0.44‐1.19) 0.200 | ||||
III‐IV | 1.29 (0.36‐4.62) 0.698 | 0.68 (0.44‐1.04) 0.074 | 1.00 | 0.71 (0.47‐1.07) 0.106 | 1.37 (0.38‐4.92) 0.626 | 0.78 (0.54‐1.13) 0.184 | ||||
Lymph node status | ||||||||||
Positive | 1.23 (0.30‐4.98) 0.775 | 0.69 (0.43‐1.10) 0.117 | 1.00 | 0.72 (0.46‐1.13) 0.151 | 1.31 (0.32‐5.29) 0.709 | 0.78 (0.52‐1.17) 0.229 | ||||
Negative | 0.59 (0.07‐5.01) 0.626 | 0.70 (0.40‐1.22) 0.208 | 1.00 | 0.69 (0.40‐1.19) 0.185 | 0.62 (0.07‐5.31) 0.665 | 0.71 (0.43‐1.18) 0.187 | ||||
Type of cancer | ||||||||||
SCC | 0.95 (0.18‐4.88) 0.947 | 0.73 (0.45‐1.18) 0.200 | 1.00 | 0.74 (0.46‐1.19) 0.211 | 1.00 (0.19‐5.14) 0.999 | 0.78 (0.50‐1.20) 0.253 | ||||
AC | 1.88 (0.51‐6.86) 0.342 | 0.74 (0.45‐1.21) 0.230 | 1.00 | 0.81 (0.50‐1.29) 0.375 | 1.97 (0.54‐7.21) 0.304 | 0.90 (0.59‐1.36) 0.619 | ||||
SCLC | 0.83 (0.10‐7.02) 0.863 | 0.54 (0.28‐1.06) 0.073 | 1.00 | 0.56 (0.29‐1.06) 0.077 | 0.91 (0.11‐7.70) 0.930 | 0.61 (0.33‐1.10) 0.100 |
* P ≤ 0.05 value indicates statistical significance; P a adjusted for age and sex.
Bold indicates the siginificant value P ≤ 0.05 and the value of study power>0.8
Abbreviations: AC, adenocarcinoma; CI, confidence interval; ORs, odds ratios; SCC, Squamous cell carcinoma; SCLC, small cell lung cancer; TNM, tumor‐lymph node‐metastasis.