Table 1.
Summary of the two-way ANOVA results of the insulin and glucose measures during the ivGTTs.
| Blood/insulin profile measures | Sampling-points (t = 0, t = 5, etc.) | TRF | Interaction | Post hoc differences (p-value) |
|---|---|---|---|---|
| Glucose during fasting period (Figure 2A) | <0.0001 | 0.0836 | 0.3555 | |
| Glucose during feeding period (Figure 2B) | <0.0001 | 0.1865 | <0.0001 |
t = 0 AL > l-TRF (0.0162) t = 5 AL < l-TRF (0.0245) t = 10 d-TRF < l-TRF (0.0027) t = 30 AL > l-TRF (0.0134) t = 60 AL > l-TRF & d-TRF (0.0102 & 0.0450) |
| Insulin during fasting period (Figure 2D) | <0.0001 | 0.0364 | 0.0342 |
t = 5 AL < l-TRF & d-TRF (<0.0001 & 0.0320) TRF: l-TRF > AL (0.0002) |
| Insulin during feeding period (Figure 2E) | <0.0001 | 0.0089 | 0.0709 |
t = 5 d-TRF < AL & l-TRF (0.0006 & 0.0006) t = 10 d-TRF < AL & l-TRF (0.0223 & 0.0397) TRF: AL > d-TRF (0.0003) |
| Net AUC measures | (Fasting/Feeding) period | TRF | Interaction | |
| Glucose (Figure 2C) | 0.5019 | 0.8084 | 0.0031 | Fasting period: AL > d-TRF (p = 0.0383) Feeding period: l-TRF > AL (p = 0.0458) AL ZT4 > AL ZT16 (p = 0.0015) |
| Insulin (Figure 2F) | <0.0001 | 0.4962 | 0.0082 | Feeding period: d-TRF < l-TRF (p = 0.0089) AL ZT4 > AL ZT16 (p = 0.0221) d-TRF ZT4 > d-TRF ZT16 (p <0.0001) |
P-values for each of the main effects as well as the interaction are given. Post hoc differences between the groups and sleep/wake measurements are also given with their corresponding p-values.