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PolyP competes with tubulin for tau binding. FCS measurements of tubulin-bound P2-4R in the absence or presence of increasing concentrations of polyP300. For reference, the dashed lines correspond to the diffusion times measured for P2-4R with 5 μM tubulin (upper), P2-4R with 20 μM polyP300 (middle), and P2-4R in buffer (lower). Data points are the SEM of three independent measurements.
