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. 2019 Jul 16;117(4):751–766. doi: 10.1016/j.bpj.2019.07.011

Figure 5.

Figure 5

Experimental voltage-dependent profile structure for water within the KvAP-POPC membrane. (A) For reference, the nSLD(z) profiles for specimen S2 and an aqueous solvent contrast of 90% D2O/10% H2O from Fig. 4 are shown juxtaposed to better delineate those more relevant regions of the membrane profile exhibiting changes in the ΔnSLD(z) profile for water only (vertical arrows). (B) The double-difference ΔΔnSLD(z) profile for solvent contrasts of 90% D2O/10% H2O minus 60% D2O/40% H2O and for hyperpolarizing minus depolarizing transmembrane voltages is shown for specimen S2. The estimated errors in the double-difference ΔΔnSLD(z) profile are 2 larger than for the ΔnSLD(z) profiles shown in Fig. 4.