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. Author manuscript; available in PMC: 2019 Aug 28.
Published in final edited form as: ACS Appl Mater Interfaces. 2019 Apr 12;11(16):14647–14659. doi: 10.1021/acsami.9b02756

Figure 2.

Figure 2.

Characterization of micelles. (A) Particle size distribution and morphology of nanoparticles. (B) ROS responsiveness confirmed by a transmission electron microscope (TEM). (C) Gel electrophoresis to confirm miRNA condensation and ROS-responsive miRNA release. (D) 1H NMR spectra of PEG-B-PAEBEA micelles after H2O2 treatment in D2O. (E) ROS production. (F) Cellular uptake of lipofectamine/FITC-miRNA and polymer/FITC-miRNA. (G) FRET effect is demonstrated via the reduction fluorescence intensity of donor at 520 nm with increased fluorescence of acceptor at 600 nm.