Binned scatterplot comparing vertical distance (horizontal axis, in mm
from horizontal midline of the optic nerve head (ONH)) to mass density (vertical
axis, ρ, in g/cm3) for control eyes (A,B) and contralateral
myopic eyes (C,D) in vertically-sectioned guinea pig eyes from near the ONH to 5
mm away in the periphery. Top panels represent superior distance and bottom
panels represent inferior distance from the ONH horizontal midline. Each dot
represents the mean from up to 12 ROIs from 6 animals measured at the given
distance. Red line is the linear regression trendline for N = 233 – 251
data points. Vertical dashed line notes upper boundary of the
“proximal” region. Arrow marks approximate location of the central
axis of the eye.