Table 2.
CD4+ T-cell count and CD4/CD8 ratio dynamics among three groups
| Time post-HAART (year) | Case (n) | CD4+ count (cells/μl)a | χ2 | P value | CD4/CD8 ratio | χ2 | P value |
|---|---|---|---|---|---|---|---|
| INRs group | |||||||
| 0 | 88 | 52 (23,93) | 0.09 (0.05,0.15) | ||||
| 0.5 | 88 | 115 (82,154) | 65.636 | < 0.001 | 0.16 (0.11,0.24) | 46.545 | < 0.001 |
| 1 | 88 | 127 (97,176) | 5.628 | 0.018 | 0.19 (0.14,0.27) | 13.136 | < 0.001 |
| 2 | 88 | 145 (119,173) | 1.943 | 0.0163 | 0.23 (0.16,0.31) | 10.227 | 0.001 |
| 3 | 87 | 175 (139,214) | 26.793 | < 0.001 | 0.27 (0.19,0.43) | 29.897 | < 0.001 |
| 4 | 86 | 191 (135,234) | 2.977 | 0.084 | 0.33 (0.22,0.53) | 15.070 | < 0.001 |
| 5 | 56 | 185 (141,226) | 0.891 | 0.345 | 0.30 (0.22,0.49) | 1.786 | 0.181 |
| 6 | 37 | 206 (151, 264) | 1.324 | 0.250 | 0.33 (0.23,0.46) | 0.027 | 0.869 |
| 7 | 32 | 199 (142, 250) | 0.032 | 0.857 | 0.36 (0.24,0.50) | 6.125 | 0.013 |
| 8 | 14 | 210 (140,346) | 0.286 | 0.593 | 0.45 (0.29,0.72) | 0.286 | 0.593 |
| IIRs group | |||||||
| 0 | 119 | 175 (74, 270) | 0.17 (0.10,0.29) | ||||
| 0.5 | 119 | 255 (187, 337) | 49.824 | < 0.001 | 0.31 (0.17,0.48) | 85.723 | < 0.001 |
| 1 | 119 | 290 (220, 393) | 28.508 | < 0.001 | 0.37 (0.21,0.56) | 17.017 | < 0.001 |
| 2 | 119 | 332 (271, 410) | 16.407 | < 0.001 | 0.41 (0.27,0.65) | 28.508 | < 0.001 |
| 3 | 118 | 366 (292, 483) | 18.880 | < 0.001 | 0.48 (0.33,0.72) | 36.915 | < 0.001 |
| 4 | 111 | 412 (308, 522) | 3.973 | 0.046 | 0.55 (0.36,0.71) | 3.252 | 0.071 |
| 5 | 75 | 418 (309, 501) | 1.613 | 0.204 | 0.52 (0.37,0.78) | 3.853 | 0.050 |
| 6 | 51 | 449 (348, 542) | 7.078 | 0.008 | 0.57 (0.38,0.70) | 1.588 | 0.208 |
| 7 | 41 | 456 (332, 630) | 0.220 | 0.639 | 0.64 (0.47,0.77) | 5.488 | 0.019 |
| 8 | 25 | 464 (333, 677) | 1.960 | 0.162 | 0.67 (0.55,0.86) | 1.960 | 0.162 |
| IRs group | |||||||
| 0 | 73 | 314 (254, 384) | 0.31 (0.25,0.38) | ||||
| 0.5 | 73 | 472 (386, 587) | 50.973 | < 0.001 | 0.52 (0.40,0.83) | 50.973 | < 0.001 |
| 1 | 73 | 529 (460, 680) | 26.889 | < 0.001 | 0.62 (0.45,0.93) | 14.918 | < 0.001 |
| 2 | 73 | 631 (574, 765) | 30.260 | < 0.001 | 0.74 (0.55,1.00) | 38.479 | < 0.001 |
| 3 | 73 | 620 (542, 763) | 2.000 | 0.157 | 0.75 (0.61,1.14) | 7.247 | 0.007 |
| 4 | 70 | 657 (528, 818) | 5.714 | 0.017 | 0.83 (0.65,1.06) | 1.429 | 0.232 |
| 5 | 46 | 656 (569, 737) | 3.130 | 0.077 | 0.81 (0.63,0.94) | 1.391 | 0.238 |
| 6 | 26 | 646 (491, 805) | 0.000 | 1.000 | 0.85 (0.72,1.00) | 2.462 | 0.117 |
| 7 | 18 | 640 (488, 841) | 2.000 | 0.157 | 0.79 (0.71,1.15) | 0.222 | 0.637 |
| 8 | 10 | 687 (569, 801) | 0.400 | 0.527 | 0.80 (0.58,0.98) | 0.400 | 0.527 |
apresented as median (P25, P75)