Table 3.

Performance of the highly sensitive rapid diagnostic test by malaria prevalence

	Very low transmission (prevalence < 5%)			Low-moderate transmission (prevalence 5 to < 20%)			High transmission (prevalence 20–50%)
	HS-RDT			HS-RDT			HS-RDT
	Positive	Negative	Total	Positive	Negative	Total	Positive	Negative	Total
PCR positive	14	18	32	92	206	298	85	82	167
PCR negative	77	777	854	230	1916	2146	72	229	301
Total	91	795	886	322	2122	2444	157	311	468
PCR prevalence	3.6 (2.5–5.1)			12.2 (10.9–13.5)			35.7 (31.3–40.2)
Sensitivity (95% CI)	43.8 (26.4–62.3)			30.9 (25.6–36.1)			50.9 (43.3–58.5)
Specificity (95% CI)	90.9 (89.1–92.9)			89.3 (87.9–90.6)			76.1 (71.3–80.9)
Positive predictive value (95% CI)	15.4 (8.7–24.5)			28.6 (23.6–33.5)			54.1 (46.4–61.9)
Negative predictive value (95% CI)	97.7 (96.4–98.7)			90.3 (89.0–91.6)			73.6 (68.7–78.5)