Table 2.

Cox regression analysis for overall survival and recurrence-free survival

Variable	Univariate analysis			Multivariate analysis
	HR	95%CI	P	HR	95%CI	P
(A) Overall survival
T stage
T3–4 vs T1–2	7.417	4.985–11.035	< 0.001	2.531	1.547–4.141	< 0.001
Lymph-node status
N1–2 vs N0	7.141	4.681–10.895	< 0.001	3.969	2.431–6.482	< 0.001
Distant metastasis
M1 vs M0	13.621	7.747–23.946	< 0.001	3.809	2.074–6.995	< 0.001
Fuhrman grade
G3–4 vs G1–2	4.594	3.067–6.883	< 0.001	1.946	1.198–3.161	0.007
CR-1 expression
High vs low	7.031	4.068–12.152	< 0.001	6.518	3.689–11.516	< 0.001
(B) Recurrence-free survival
T stage
T3–4 vs T1–2	5.380	3.409–8.490	< 0.001	2.051	1.167–3.606	0.013
Lymph-node status
N1–2 vs N0	6.320	3.836–10.410	< 0.001	4.818	2.581–8.995	< 0.001
Fuhrman grade
G3–4 vs G1–2	3.685	2.302–5.897	< 0.001	1.783	1.045–3.043	0.034
CR-1 expression
High vs low	5.133	3.058–8.616	< 0.001	5.638	3.274–9.711	< 0.001

Abbreviations: HR Hazard ratio, 95% CI 95% confidence interval