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. 2019 Aug 28;19:223. doi: 10.1186/s12935-019-0938-3

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Western blot analysis of total protein extracts of A-375 (a) and SK-MEL-28 (b) cells treated for 48 h with Dabrafenib and Trametinib, alone and in combination, and DMSO as control. The protein species were detected at the expected molecular weights per their datasheets, as follows: β-tubulin ~ 55 kDa; tissue factor (TF) ~ 35 kDa. Protein expression was normalized to their loading control (β-tubulin)