Table 2.
Top-10 epistatic interactions associated with AMD captured by AntEpiSeeker, SNPRuler, BOOST, MDR
| ID/Methods | AntEpiSeeker | SNPRuler | BOOST | MDR | ||||
|---|---|---|---|---|---|---|---|---|
| SNP1 | SNP2 | SNP1 | SNP2 | SNP1 | SNP2 | SNP1 | SNP2 | |
| 1 | rs1329428 | rs9328536 | rs10503790 | rs6928748 | rs9316435 | rs10503216 | rs555174 | rs380390 |
| References | Sun et al. 2017, Kwon et al. 2014, Tuo et al. 2016 | – | – | – | ||||
| 2 | rs4880042 | rs718309 | rs657618 | rs7908635 | – | – | rs10507949 | rs10511467 |
| References | – | – | – | – | ||||
| 3 | rs9316435 | rs10503216 | rs10512781 | rs10510099 | – | – | rs1293449 | rs380390 |
| References | – | – | – | – | ||||
| 4 | rs10505112 | rs10512174 | rs215389 | rs903645 | – | – | rs961360 | rs380390 |
| References | – | – | – | – | ||||
| 5 | rs1359634 | rs1740752 | rs4526387 | rs2105250 | – | – | rs10511467 | rs1394608 |
| References | – | – | – | – | ||||
| 6 | rs1535891 | rs6598991 | rs485412 | rs10497257 | – | – | rs724972 | rs380390 |
| References | – | – | – | Tuo et al. 2016 | ||||
| 7 | rs9294603 | rs6540592 | rs1677189 | rs4947673 | – | – | rs261796 | rs380390 |
| References | – | – | – | – | ||||
| 8 | rs943653 | rs4128956 | rs3829918 | rs727200 | – | – | rs1510134 | rs380390 |
| References | – | – | – | – | ||||
| 9 | rs1233255 | rs860309 | rs7533063 | rs10484087 | – | – | rs1742923 | rs380390 |
| References | – | – | – | – | ||||
| 10 | rs404199 | rs10510895 | rs1489402 | rs10484087 | – | – | rs1146382 | rs380390 |
| References | – | – | – | – | ||||