FIG 4.

Vascular and molecular alterations associated with YAP deletion. (A) IB4 staining of P5 retinal flat mounts from YAP^+/+, EC-ΔYAP, and UB-ΔYAP mice. (B to E) Relative mRNA levels of YAP target genes in retinal lysates from YAP^+/+, EC-ΔYAP, and UB-ΔYAP mice. Expression of TAZ was also included. The mRNA levels in YAP^+/+ mice were set to 1. Each measurement was performed in triplicate (n = 3). (F) Relative mRNA levels of VEGF-A and VEGF-R2 in retinal lysates from YAP^+/+, EC-ΔYAP, and UB-ΔYAP mice (n = 3).