Table 2.
Results Showing the Optimal Thresholds to Identify the Baseline Ischemic Core in Patients Treated With Thrombectomy Compare the Alteplase Alone
| AUC | |||||
|---|---|---|---|---|---|
| (95% CI) | Sensitivity | Specificity | Volume Difference | ||
| (CTP‐DWI) | |||||
| (median, IQR) (ml) | p | ||||
| Thrombectomy patients | |||||
| CBF <15% | 0.84 (0.79, 0.89) | 0.94 | 0.79 | 1.52 (–20.89, 26.79) | 0.187 |
| CBF <20% | 0.89 (0.85, 0.94) | 0.91 | 0.87 | 2.61 (–4.30, 8.78) | 0.867 |
| CBF <25% | 0.86 (0.81, 0.91) | 0.86 | 0.93 | 8.59 (–16.05, 24.51) | 0.135 |
| CBV <25% | 0.73 (0.68, 0.81) | 0.92 | 0.77 | −1.38 (–17.16, 17.31) | 0.610 |
| CBV <30% | 0.84 (0.79, 0.88) | 0.9 | 0.82 | 4.65 (1.57, 9.78) | 0.435 |
| CBV <35% | 0.82 (0.77, 0.85) | 0.87 | 0.85 | 8.53 (–37.46, 53.35) | 0.706 |
| Alteplase patients | |||||
| CBF <25% | 0.81 (0.74, 0.89) | 0.86 | 0.79 | −9.50 (–26.95, 10.75) | 0.095 |
| CBF <30% | 0.83 (0.77, 0.85) | 0.84 | 0.77 | −1.52 (–11.89, 13.79) | 0.53 |
| CBF <35% | 0.79 (0.76, 0.83) | 0.81 | 0.76 | −1.18 (16.94, 18.05) | 0.844 |
| CBV <35% | 0.78 (0.66, 0.82) | 0.80 | 0.81 | −12.75 (–59.87, 24.52) | 0.272 |
| CBV <40% | 0.8 (0.76, 0.83) | 0.82 | 0.77 | 1.27 (–1.23, 4.9) | 0.019 |
| CBV <45% | 0.74 (0.69, 0.79) | 0.83 | 0.68 | 0.85 (–12.59, 9.12) | 0.435 |
CTP = computed tomography perfusion; DWI = diffusion‐weighted imaging; CBF = cerebral blood flow; CBV, cerebral blood volume; AUC = area under the curve; CI, confidence interval; IQR = interquartile range.