Skip to main content
. 2019 Aug 21;10:1940. doi: 10.3389/fmicb.2019.01940

Table 1.

Model parameters and baseline values.

Expression Description Value
rCj Growth rate for Campylobacter strain j. 0.3009
r2 Growth rate for other bacteria (B). 0.1407
α1 Campylobacter competition coefficient. 0.9744
α2 Other bacteria competition coefficient. 1
γCj Rate of inhibition by host defense peptides (P) on Campylobacter strain j. 0.6358
ξj Rate of host defense peptide growth in response to Campylobacter strain j. 0.7411
b Rate of broiler shedding Campylobacter into the environment, Ej. 10
Ω Total environmental carrying capacity of Campylobacter. 200, 000*
dCj Death rate of Campylobacter strain j. 0.0185
d2 Death rate of other bacteria. 0.0212
d3 Decay rate of host defense peptides. 0.0463
d4 Decay rate of maternal antibodies. 0.0046
d5 Death rate of Campylobacter in the environment. 0.05
βCj Rate of inhibition by other bacteria on Campylobacter strain j. 0.0276
σCj Rate of inhibition by maternal antibodies on Campylobacter strain j. 0.0661
ηCj Scaling factor applied to stochastic Campylobacter growth in the gut. 0.01
ηBCj Scaling factor applied to stochastic Campylobacter inhibition by other competing bacteria. 0.0847
η2 Scaling factor applied to stochastic competing bacteria (B) growth. 0.01
η3 Scaling factor applied to stochastic host defense peptide (P) growth. 0.01
η4 Scaling factor applied to stochastic maternal antibody (M) decay. 0.01
η5 Scaling factor applied to stochastic Campylobacter growth in the environment. 0.01

Descriptions for all parameter values appearing in the final stochastic model, Equations (14–18). Baseline values are given, used for model validation and simulation case studies. Values were calculated by using simulated annealing to identify a parameter set that best fits the experimental data of Achen et al. (1998) (Figure 2). See Appendix S2 in Supplementary Material for an explanation of simulated annealing.

*

Ω value is dependent on the experiment specifics for model validation, but flock case studies consider a flock of 400 chickens, and an Ω value of 200,000.