Table 5.
Effect of MeOH and n-BuOH extracts of V. nubicum on acetic acid induced abdominal constriction in rats.
Groups | Treatment (mg/kg) | Number of writhings for 30 min | Inhibition (%) |
---|---|---|---|
I | Control | 97.5 ± 3.5 | |
II | MeOH extract (200 mg/kg b.w.) | 48.25 ± 4.10* | 50.5% |
III | MeOH extract (400 mg/kg b.w.) | 37.47 ± 2.44*a,b | 61.57% |
IV | n-BuOH extract (100 mg/kg b.w.) | 42.80 ± 2.16*a | 56.10% |
V | Butanol extract n-BuOH extract (200 mg/kg b.w.) | 32.70 ± 3.00*b | 66.46% |
VI | Aspirin (100 mg/kg b.w.) | 38.11 ± 2.40*a | 60.91% |
Note: Aspirin is used as a reference.
*Significant at p < 0.05, Groups (II–VI) were compared with group (I). Data shown are mean ± standard deviation of number of observations within each treatment. Data followed by the same letter are not significantly different at p ≤ 0.05.