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. Author manuscript; available in PMC: 2019 Aug 28.
Published in final edited form as: Toxicol Lett. 2018 Mar 1;291:194–199. doi: 10.1016/j.toxlet.2018.03.001

Table 1.

Effect of Triclosan on mean (+/− SEM) organ/accessory sex tissue weights of castrated male rats in the Hershberger assay.

Treatment BW (g) GP (mg) SV (mg) VP (mg) CG (mg) LABC (mg) Liver (g) Thyroid (mg) N
Control+(sc) Oil 311 ± 8.11 44.9 ± 1.73 36.9 ± 3.79 16.0 ± 0.22 4.53 ± 0.57 166 ± 8.84 13.8 ± 1.52 19.8 ± 2.47 5
Control+(sc) TP 0.2mg/kg 317 ± 12.3 74.1 ± 3.40 173 ± 14.0 70.3 ± 7.85 21.9 ± 2.11 325 ± 22.1 14.2 ± 0.84 22.4 ± 1.30 7
TCS 50 mg/kg+(sc) Oil 300 ± 9.40 45.6 ± 1.87 30.6 ± 5.45 13.5 ± 1.72 4.98 ± 1.05 153 ± 9.03 12.3 ± 0.34 18.6 ± 1.15 5
TCS 50 mg/kg+(sc) TP 0.2 mg/kg 315 ± 5.67 74.2 ± 2.97 206 ± 12.8 74.2 ± 4.01 24.0 ± 2.48 307 ± 9.90 15.8 ± 0.47 20.0 ± 1.21 6
TCS 200 mg/kg+(sc) Oil 308 ± 5.53 45.9 ± 3.78 29.3 ± 0.73 13.6 ± 1.04 4.86 ± 0.84 153 ± 9.30 14.8 ± 0.90 20.4 ± 0.90 5
TCS 200 mg/kg+(sc) TP 0.2 mg/kg 315 ± 12.5 72.0 ± 1.91 180 ± 11.1 86.1 ± 7.17 25.4 ± 2.36 318 ± 18.2 15.0 ± 0.59 21.6 ± 1.53 6

Note: sc=subcutaneous, TP=testosterone proprionate, BW=body weight, GP=glans penis, SV=seminal vesicle, CG=coagulating gland, LABC=levitor ani plus bulbocavernosus muscle. None of the treatment mean weights were significantly different from the corresponding control (oil or TP).