Skip to main content
. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: J Trauma Acute Care Surg. 2019 Sep;87(3):582–589. doi: 10.1097/TA.0000000000002385

Table 4 –

Predictive Accuracy of Prolonged Conventional Coagulation Assays (CCA) for Deficiency of Coagulation Factors

CCA Deficiency of: Sensitivity
%		 Specificity
%		 PPV
%		 NPV
%
INR>1.3 Extrinsic Pathway (Factor
VII)		 100% 62.70% 4.40% 100%
Common Pathway 86.70% 77.80% 56.50% 94.60%
aPTT>34 sec Intrinsic Pathway 100% 73.20% 21.10% 97.20%
Common Pathway 93.30% 88.90% 73.70% 100%
INR>1.3 and
aPTT>34 sec		 Intrinsic Pathway 75.00% 73.20% 16.70% 97.60%
Extrinsic Pathway (Factor
VII)		 100% 73.20% 5.60% 100%
Common Pathway 86.70% 88.90% 72.20% 95.20%

PPV: positive predictive value; NPV: negative predictive value; INR: International Normalized Ratio; aPTT: activated Partial Thromboplastin Time