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. 2019 Aug 28;14(8):e0221477. doi: 10.1371/journal.pone.0221477

Fig 3. OSM induces a pro-inflammatory vascular phenotype in APOE*3Leiden.CETP mice.

Fig 3

Plasma E-selectin, MCP-1 and SAA (A-C) were measured at multiple time points during the study. Monocyte adhesion (D) and endothelial ICAM-1 expression were assessed per cross-section in the aortic root area (E). Data represent mean ± SD (n = 12–20). The Kruskal-Wallis test was used to test for overall significance. If significant, the Mann-Whitney U test was performed to test which treatment groups were significantly different from the control group. Except for monocyte adhesion, which was tested with a t-test. Rejection criteria were adjusted using a Bonferroni-Holm correction. ‡ p<0.05 compared to 10 μg/kg/day; **p<0.01 compared to control; ‡‡ p<0.01 compared to 10 μg/kg/day; ***p<0.001 compared to control.